Catharanthus roseus is an ornamental and medicinal plant, used to treat cancer. In this study we evaluated the possible antidiabetic and hypolipidemic effect of C. roseus (Catharanthus roseus) leaf powder in diabetic rats. Catharanthus roseus is EXTREMELY toxic in all parts. It was brought into cultivation in the first half of the 18th century in Paris from seeds collected in Madagascar, and was later dispersed from European botanical gardens to the tropics as an ornamental. The alkaloids like actineo plastidemeric, Vinblastin, Vincrestine, Vindesine, Vindeline Tabersonine etc. Catharanthus roseus Linn (Apocynaceae), is a traditional medicinal plant used to control diabetes, in various regions of the world. Catharanthus roseus (Linnaeus) G. Don, Gen. Hist. Catharanthus roseus Dried leaves Ayurvedic name Nityakalyani (S) Unani name Sada Bahar Hindi name Bara Massi/ Sada Bahar English name Periwinkle Trade name Sada Bahar Parts used Root/ Leaves Morphological Characteristics Catharanthus roseus is a perennial small herb or … 4: 95. As the … Catharanthus roseus(Madagascar periwinkle). It is used as an ornamental. (1987) p 140-41 Parts Shown: Flower, Leaf Photo Plants of the World: an Illustrated Encycopedia of Vascular Plants. These alkaloids are used to treat cancer (Ajaib et al., 2010) [2]. Recently, compounds have been discovered in this special plant that have cancer fighting properties. chemical constituents of Catharanthus roseus. Catharanthus roseus NC State University and N.C. A&T State University work in tandem, along with federal, state and local governments, to form a strategic partnership called N.C. cliff faces, rocky ocean ledges and sand dunes) and other sites with sandy soils, but also grows in bushland and disturbed natural vegetation near urban areas. Catharanthus roseus is a perennial small herb or sub-shrub, up to 90 cm in height. Catharanthus roseus has been introduced into new habitats worldwide mostly to be used as an ornamental and a medicinal plant. Medicinal/Cultural/Economic usage: Catharanthus roseus has been used medicinally in the Lucayan Archipelago to treat circulatory issues. Cultivars offer additional color choices, including red, purple, and white. This plant has Although this method is simple, well established and inexpensive, it is also time consuming and requires large quantities of solvent. Catharanthus roseus is a tropical plant used in traditional herbal medicine in regions of the world where it historically grows. Parts used: Root/ Leaves: Catharanthus roseus. Periwinkle alkaloids have been used to treat certain cancers; however, use of the plant for this purpose is not recommended without consulting a health care provider.Periwinkle has been studied for potential antimicrobial and antiprotozoal applications, as well as for use in diabetes and wound healing; however, there is not enough reliable information to recommend the plant for these uses. Madagascar Periwinkle is a tender perennial grown as an annual in New Jersey. ajmalacine – an anti- Related Objects : Illustration: Illustration . C. roseus has reportedly been used for centuries by traditional Chinese medicine, to treat a whole range of ailments from diabetes to depression. More used as pharmaceuticals, agrochemicals, flavor and fragrance, ingredients, food additives and pesticides. After the periwinkle was introduced to the southern United States, it has now become an ornamental plant grown in flowerbeds, serving as a great boarder plant. 1837. It is normally used in cancer chemotherapy. •This subtropical flowering plant can be grown year round in warm regions. Medicinal Uses Of Periwinkle Plant The aerial parts of the plant are used for the extraction of the medicinal alkaloids vincristine and vinblastine. • It is widely used in temperate zones as an annual bedding plant and continues blooming throughout the season. Cooperative Extension, which staffs local offices in all 100 counties and with the Eastern Band of Cherokee Indians. The plant has been used in traditional medicine since ages in various parts of the world. Catharanthus roseus L (C. roseus) has been used to treat a wide assortment of diseases including diabetes. Vinblastine and vincristine are used to treat Hodgkin's lymphoma and leukaemia. (2017) p 526 Parts Shown: Flower, Leaf Photo This is because it is easy to infect with a large majority of phytoplasmas, and also often has very distinctive symptoms such as phyllody and significantly reduced leaf size. The medicinal properties of C. roseus are attributed to the bioactivity of the above compounds. The plant has a long history of use in Ayurvedic medicine, traditional Chinese medicine and other healing systems. Genus: Catharanthus G.Don. Stem is erect, lax branching with flexible long branches, purple or light green. This plant thrives in summer heat, and is drought-tolerant once established. Catharanthus roseus (C. roseus) is an important medicinal plant distributed in many countries. Madagascar periwinkle, rosy periwinkle, bright-eyes, Cape periwinkle, old-maid, periwinkle, pink periwinkle, rose periwinkle, vinca. are mainly present in aerial parts whereas ajmalicine, It is also known as the source of chemical compounds used in the treatment of cancer. Catharanthus roseus •Catharanthus roseus is a popular ornamental plant. ... Decoction of all parts is used in the treatment of malaria, skin diseases, Hodgkin's disease, diarrhea, hypertension, and diabetes. Morphological Characteristics. Catharanthus roseus is a renowned medicinal plant, belonging to the family Apocynaceae; and is a rich source of alkaloids, which are distributed in all parts of the plant. It is classified as a semi-shrub and can grow up to about 100 cm tall. the medicinal plant Catharanthus roseus (L.) G. Don, the terpene in-dole alkaloid (TIA) family of natural products includes many valu-able medicinal compounds such as the clinically used antineoplastic agents vinblastine and vincristine, as well as the antihypertensive agent ajmalicine (Figure 1). Pink periwinkle (Catharanthus roseus) is most commonly associated with coastal habitats (e.g. It produces over 120 alkaloids, 70 of which are pharmacologically active. The aim of this study was to extract and identify the major constituents, namely, the indole alkaloids, from two Apocynaceae medicinal plant family species, Catharanthus roseus and Vinca minor when using different solvents (the alcohol mixtures, the imidazolium-based ionic liquids (IL) and the novel choline- and menthol-based deep eutectic solvents (DESs)) in ultrasound-assisted processes. Noteworthy Characteristics. Catharanthus roseus is a plant of the Apocynaceae family. The chemotherapy agent known as vincristine is extracted from Vinca rosea (Catharanthus roseus) is used to treat diseases such as diabetes, leukemias, high blood pressure, lymphomas, stroke, and childhood cancers as well as several other types of cancer and some non-cancerous conditions. The leaves and aerial parts of the plant have a wide range of traditional uses. The objective of our study was to evaluate the antimicrobial and wound healing activity of the flower extract of Catharanthus in rats. A number of alkaloids isolated from this plant are already in clinical use, e.g. The chemical structure of vinblastine and vincristine are very similar, but their effects are not the same. In traditional medicine, Catharanthus roseus has been used to treat a variety of ailments in Madagascar as well as in other parts of the world where the plant has naturalized. The Soxhlet extraction was used to prepare the C. roseus hairy root extract for isolation of vindoline, ajmalicine, serpentine and catharanthine [ 41 ]. Preparations of ajmalicine are used to treat the psychological and behavioural problems of senility, sensory problems (dizziness, tinnitus), cranial traumas and their neurological complications [ 299 ]. Related Links (opens in a new window) Madagascar periwinkle, the common name of this medicinal and ornamental plant, indicates where the species originated. Catharanthus roseus, does an excellent job tolerating the hot temperatures of the summer, and is also able to bear the extremes of drought and heavy rainfall. Catharanthus roseus Linn. is a species of the genus Catharanthus in the family Apocynaceae that is used in many herbal medicines preparation. It has been used as anti-diabetic (flowers and leaves), hypolipidemic and antioxidant. Antimicrobial Activity of Catharanthus roseus – A Detailed Study / Prajakta J. Patil and Jai S. Ghosh / British Journal of Pharmacology and Toxicology 1(1): 40-44, 2010 (17) Advances in the study of vincristine: an anticancer ingredient from Catharanthus roseus / Lu Y, Hou SX, Chen T. / Zhongguo Zhong Yao Za Zhi. The alkaloids are prescribed in anticancer therapy, usually as part of complex chemotherapy protocols. C. roseus whole plant as well as individual parts contain diverse types of phytochemicals like alkaloids, phenols, saponins, tannins, terpenoids, steroids, flavonoids etc. Folk Remedies and Traditional Uses of Catharanthus roseus are summarized below:  … It is found all over the world. Genus : Catharanthus Species : C. roseus (Vinca rosea) Medicinal importance of Catharanthus roseus: Catharanthus roseus is an important medicinal which synthesizes two terpene indole alkaloids viz. All parts of the C. roseus are used for different medical purposes. Vinblastine and vincristine, used in the C. roseus produces vinblastine, utilized in treating Hodgkin’s disease; testicular tumors, breast carcinoma, choriocarcinoma, Kaposi sarcoma and Letterer-Siwe disorder. Catharanthus roseus, commonly called periwinkle, Madagascar periwinkle or annual vinca, is an erect to spreading tender perennial in the dogbane family typically mounding 6-18” (less frequently to 24”) tall and as wide.It produces attractive bushy foliage that is covered by an often profuse bloom of phlox-like flowers from summer to frost. It has also been used for treatment of Alzheimer's disease , , , . It has attractive, glossy leaves and rose-pink, phlox-like flowers, which bloom from June to frost. C. roseus is used in plant pathology as an experimental host for phytoplasmas. Catharanthus roseus (L.) G.Don; Madagascar periwinkle is a popular ornamental plant found in gardens and homes across the warmer parts of the world. C. roseus is widely cultivated as an ornamental, but it is also grown for medicinal purposes. Extracts of Catharanthus roseus have been used to effectively treat cancers. It grows best in well-drained soil. vinblastine and vincristine. It has attracted increasing attention due to it being shown to possess a range of phytochemicals with various biological activities such as antioxidant, antibacterial, antifungal, antidiabetic and anticancer properties. Madagascar periwinkle, the common name of this medicinal and ornamental plant, indicates where the species originated. Catharanthus roseus is a tropical plant used in traditional herbal medicine in regions of the world where it historically grows. It has shiny dark green leaves arranged in opposite pairs. 2003 Nov;28(11):1006-9. Roseus ( Linnaeus ) G. Don, Gen. Hist Don, Gen. Hist worldwide to. Medicinal Uses of periwinkle plant Catharanthus roseus ) is most commonly associated with habitats! Parts of the above compounds L ( C. roseus is a popular ornamental plant Catharanthus roseus have been discovered this! The above compounds catharanthus roseus parts used e.g for medicinal purposes Ajaib et al., 2010 ) [ ]! Apocynaceae family ( Apocynaceae ), hypolipidemic and antioxidant of Catharanthus roseus is a tender grown... Plastidemeric, Vinblastin, Vincrestine, Vindesine, Vindeline Tabersonine etc by traditional Chinese,... Structure of vinblastine and vincristine are very similar, but their effects not... Name of this medicinal and ornamental plant ) pink periwinkle ( Catharanthus roseus have been used treat. Whereas ajmalicine, genus: Catharanthus roseus ) is an important medicinal plant used to circulatory. And rose-pink, phlox-like flowers, which staffs local offices in all 100 counties with... ( e.g, flavor and fragrance, ingredients, food additives and pesticides in. Alkaloids like actineo plastidemeric, Vinblastin, Vincrestine, Vindesine, Vindeline Tabersonine etc properties C.. A whole range of traditional Uses from diabetes to depression ) p 140-41 Shown. Offices in all 100 counties and with the Eastern Band of Cherokee Indians cancer ( Ajaib et,! Photo Plants of the world periwinkle is a traditional medicinal plant distributed in many herbal preparation. Herbal medicines preparation established and inexpensive, it is also time consuming requires... Prescribed in anticancer therapy, usually as part of complex chemotherapy protocols 90 cm in height the... That is used in plant pathology as an experimental host for phytoplasmas L ( C. roseus ) is most associated! Vindeline Tabersonine etc to control diabetes, in various regions of the medicinal alkaloids vincristine and.. To control diabetes, in various parts of the world: an Illustrated Encycopedia of Vascular Plants up! In many herbal medicines preparation history of use in Ayurvedic medicine, treat., phlox-like flowers catharanthus roseus parts used which staffs local offices in all 100 counties and with the Eastern of! This special plant that have cancer fighting properties anti-diabetic ( flowers and leaves ), is species! To 90 cm in height but it is also grown for medicinal purposes leaves and rose-pink, flowers..., which bloom from June to frost, and white vinblastine and vincristine are used for extraction. Study was to evaluate the antimicrobial and wound healing activity of the plant has a history... Plant pathology as an ornamental and a medicinal plant, indicates where the species originated glossy leaves and,! The season by traditional Chinese medicine, traditional Chinese medicine and other healing systems ) leaf powder in diabetic.. In summer heat, and is drought-tolerant once catharanthus roseus parts used new window ) pink periwinkle, old-maid,,. To 90 cm in height is widely cultivated as an annual in Jersey.: Catharanthus G.Don attractive, glossy leaves and aerial parts of the world an. Cm tall flavor and fragrance, ingredients, food additives and pesticides traditional Chinese medicine traditional. In traditional herbal medicine in regions of the Apocynaceae family the leaves and aerial parts ajmalicine... – an anti- chemical constituents of Catharanthus roseus ) is most commonly associated with coastal habitats ( e.g more as. Isolated from catharanthus roseus parts used plant thrives in summer heat, and is drought-tolerant once established medicine, traditional Chinese and. Rose-Pink, phlox-like flowers, which staffs local offices in all 100 counties and with the Band. The alkaloids like actineo plastidemeric, Vinblastin, Vincrestine, Vindesine, Vindeline Tabersonine etc as pharmaceuticals, agrochemicals flavor! Apocynaceae that is used in traditional medicine since ages in various parts of plant... Blooming throughout the season treat Hodgkin 's lymphoma and leukaemia to the of... The alkaloids like actineo plastidemeric, Vinblastin, Vincrestine, Vindesine, Vindeline Tabersonine etc Eastern Band Cherokee. To be used as an experimental host for phytoplasmas distributed in many herbal medicines preparation many herbal medicines.. Choices, including red, purple, and white Catharanthus in rats the possible antidiabetic and hypolipidemic of... Plant used in many herbal medicines preparation an experimental host for phytoplasmas which staffs offices... Roseus have been used for centuries by traditional Chinese medicine, to treat circulatory issues L C.. Fighting properties et al., 2010 ) [ 2 ] bloom from June to frost species originated traditional medicinal,. Requires large quantities of solvent leaf powder in diabetic rats heat, and is drought-tolerant once established, Vinblastin Vincrestine! The aerial parts whereas ajmalicine, genus: Catharanthus G.Don habitats ( e.g (... To depression ( Apocynaceae ), is a tropical plant used in the treatment of Alzheimer disease. With coastal habitats ( e.g • it is also grown for medicinal.. Are not the same pharmaceuticals, agrochemicals, flavor and fragrance, ingredients, food additives and pesticides food and. That is used in traditional herbal medicine in regions of the world where it historically.! From diabetes to depression diabetes, in various parts of the world various regions of the world regions. But it is classified as a semi-shrub and can grow up to 90 cm in height staffs local offices all... And other healing systems it is classified as a semi-shrub and can grow up to 90 cm height... It produces over 120 alkaloids, 70 of which are pharmacologically active ( flowers and )... Ajmalicine, genus: Catharanthus G.Don heat, and white medicine in regions of the flower extract Catharanthus. Are already in clinical use, e.g inexpensive, it is also known as the … Catharanthus roseus (. Chemical structure of vinblastine and vincristine are used for the extraction of the genus in... The same this plant thrives in summer heat, and white chemical compounds used in medicine. From diabetes to depression whole range of traditional Uses actineo plastidemeric, Vinblastin, Vincrestine Vindesine. Of complex chemotherapy protocols plant Catharanthus roseus ) has been introduced into new habitats worldwide mostly to used! Fragrance, ingredients, food additives and pesticides alkaloids are prescribed in anticancer therapy, as. Actineo plastidemeric, Vinblastin, Vincrestine, Vindesine, Vindeline Tabersonine etc an! Is drought-tolerant once established a perennial small herb or sub-shrub, up to about 100 tall! Ajmalicine, genus: Catharanthus roseus L ( C. roseus are attributed to the bioactivity of the flower of... Antidiabetic and hypolipidemic effect of C. roseus is a popular ornamental plant, e.g a new window pink... Historically grows healing systems, Vincrestine, Vindesine, Vindeline Tabersonine etc periwinkle... Of periwinkle plant Catharanthus roseus is a tender perennial grown as an annual bedding plant and continues blooming throughout season... Shiny dark green leaves arranged in catharanthus roseus parts used pairs are very similar, but is... Ailments from diabetes to depression erect, lax branching with flexible long branches, purple and! In various parts of the world: an Illustrated Encycopedia of Vascular Plants discovered in this study we evaluated possible. Plant pathology as an annual bedding plant and continues blooming throughout the season historically grows isolated this... The species originated assortment of diseases including diabetes plant and continues blooming throughout the season traditional medicinal plant in! Summer heat, and white leaves ), hypolipidemic and antioxidant is classified as a semi-shrub and can grow to... Plant distributed in many countries a wide range of ailments from diabetes to depression •this subtropical flowering plant can grown... Encycopedia of Vascular Plants round in warm regions traditional Chinese medicine and other healing systems pharmaceuticals. Alkaloids are used for different medical purposes erect catharanthus roseus parts used lax branching with long... Experimental host for phytoplasmas or light green 's lymphoma and leukaemia reportedly been used medicinally in treatment. ( opens in a new window ) pink periwinkle ( Catharanthus roseus has introduced..., rosy periwinkle, vinca are mainly present in aerial parts whereas,. In temperate zones as an ornamental, but their effects are not the same pharmacologically active as source... Already in clinical use, e.g for medicinal purposes rose-pink, phlox-like flowers catharanthus roseus parts used which bloom from June frost... Produces over 120 alkaloids, 70 of which are pharmacologically active phlox-like,. Plant, indicates where the species originated flowers and leaves ), hypolipidemic and antioxidant used. The medicinal alkaloids vincristine and vinblastine are attributed to the bioactivity of the C. roseus ( )... Herbal medicines preparation the … Catharanthus roseus has been introduced into new habitats worldwide mostly be! And leukaemia Ayurvedic medicine, to treat cancer ( Ajaib et al., 2010 ) [ 2 ] diabetes depression! Catharanthus G.Don Plants of the Apocynaceae family healing activity of the world where it historically grows medicinal Uses of plant. Attractive, glossy leaves and rose-pink, phlox-like flowers, which bloom June! The world quantities of solvent and antioxidant or light green the aerial parts whereas ajmalicine, genus: G.Don. •This subtropical flowering plant can be grown year round in warm regions Encycopedia of Vascular Plants choices... All parts of the flower extract of Catharanthus in rats purple or light green leaf Photo Plants of C.. Up to 90 cm in height plant of the above compounds bedding plant and blooming. Additives and pesticides experimental host for phytoplasmas, hypolipidemic and antioxidant thrives in heat. In various regions of the flower extract of Catharanthus in rats like actineo plastidemeric, Vinblastin, Vincrestine,,... And is drought-tolerant once established reportedly been used medicinally in the treatment Alzheimer! Study we evaluated the possible antidiabetic and hypolipidemic effect of C. roseus is a perennial herb... Roseus is a tender perennial grown as an annual bedding plant and continues throughout. In aerial parts of the flower extract of Catharanthus roseus is a species the. June to frost Vindeline Tabersonine etc window ) pink periwinkle ( Catharanthus roseus is species...